The hotel is named for the Greek goddess, Artemis, who was the goddess of the hunt, known in Roman myth as Diana. She was the twin of Apollo, illegitimate daughter of Zeus, born in secret on a floating island to avoid the wrath of Hera. Her mother, Leto, is sometimes referred to as "the hidden one" due to her need to hide from Hera. In this film, the Nurse is sort of the mother of the Hotel Artemis and she too is "hidden."
There are four patient rooms in the Hotel Artemis: Niagara, Honolulu, Accapulco and Nice. Patients assigned to these rooms are only ever referred to by that room's name. Sterling K. Brown's character is called "Waikiki," because he shares the Honolulu room with his brother.
Sterling Brown, Dave Bautista & Jeffrey Goldblum all play in Marvel Cinematic Universe (MCU) movies; Brown in "The Black Panther" Bautista in the "Guardians of the Galaxy" & "Avengers Infinity War" & Goldblum in "Thor Ragnarok".
At the end, "The Nurse" refers "Waikiki" to a "dark room" in Las Vegas. Dark room is a longstanding underworld term for an emergency room or similar medical facility where criminals can go without the police finding out. The Hotel Artemis is a dark room, albeit a very elaborate one.